Free PubMed Central (PMC) full text or preprint of each paper via links below, where available. 

  1. Chan K, Doherty KN, Alasmar S. An analysis of intrinsic base substitution patterns in diverse species reveals connections to cancer and metabolism. bioRxiv. 2019 Sep 8; Available from:

  2. Alexandrov L, Kim J, Haradhvala NJ, Huang MN, Ng AWT, Boot A, et al. The Repertoire of Mutational Signatures in Human Cancer. bioRxiv [Internet]. 2018 Jan 1; Available from:

  3. Chan K. (2018) Molecular Genetic Characterization of Mutagenesis Using a Highly Sensitive Single-Stranded DNA Reporter System in Budding Yeast. In Genome Instability: Methods and Protocols. Methods Mol Biol. 1672, 33-42. doi: 10.1007/978-1-4939-7306-4_4. PMID: 29043615.

  4. Waszak SM, Tiao G, Zhu B, Rausch T, Muyas F, Rodriguez-Martin B, et al. Germline determinants of the somatic mutation landscape in 2,642 cancer genomes. bioRxiv [Internet]. 2017 Nov 1; Available from:

  5. Wala JA, Shapira O, Li Y, Craft D, Schumacher SE, Imielinski M, et al. Selective and mechanistic sources of recurrent rearrangements across the cancer genome. bioRxiv [Internet]. 2017 Sep 14; Available from:

  6. The Cancer Genome Atlas Research Network. (2017) Integrated genomic and molecular characterization of cervical cancer. Nature. 543:378-84.

  7. Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA. (2016) The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts. PLOS Genetics. 12(10): e1006385.

  8. Chan K, Gordenin DA. (2015) Clusters of Multiple Mutations: Incidence and Molecular Mechanisms. Annual Review of Genetics. 49:243-67.

  9. Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, Malc EP, Kim Jaegil, Kwiatkowski DJ, Fargo DC, Mieczkowski PA, Getz G, and Gordenin DA. (2015) An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. Nature Genetics. 47(9):1067-72.

  10. Chan K, Resnick MA, and Gordenin DA. (2013) The choice of nucleotide inserted opposite abasic sites formed within chromosomal DNA reveals the polymerase activities participating in translesion DNA synthesis. DNA Repair. 12(11):878-89.

  11. Chan K, Sterling JF, Roberts SA, Bhagwat AS, Resnick MA, and Gordenin DA. (2012) Base Damage within Single-Strand DNA Underlies In Vivo Hypermutability Induced by a Ubiquitous Environmental Agent. PLOS Genetics. 8(12): e1003149.

  12. Chan K, Goldmark JP, and Roth MB. (2010) Suspended animation extends survival limits of Caenorhabditis elegans and Saccharomyces cerevisiae at low temperature. Molecular Biology of the Cell. 21(13): 2161-71.

  13. Chan K, Roth MB. (2008) Anoxia-induced suspended animation in budding yeast as an experimental paradigm for studying oxygen-regulated gene expression. Eukaryotic Cell. 7(10): 1795-808.